10/18/2023 0 Comments Bioptigen sd octHowever, data on normative values of the retina for wild-type C57BL/6– a common mouse model for the study of retinal diseases – is not available. Bioptigen SD-OCT technology is increasingly implemented in rodents for biometrical analysis as well as evaluation and management of retinal disorders. It contains the animal imaging mount with rodent alignment stage (a unique platform with adjusters that stereotactically secures mice within a cassette while mounted to a rotational stage) and a hand-held 840 nm SD-OCT probe (HHP) capable of axial resolutions of 5 micrometers (µm) –. Hand-held spectral domain ophthalmic imaging system (SDOIS) (Bioptigen, Inc., Durham, NC) represents an alternative non-invasive in vivo imaging device. Although SD-OCT provides non-invasive histological – grade sections of the rodent posterior segment, image acquisition is technologically cumbersome as human devices are retrofitted for animal use. With the advent of in vivo applications such as fundoscopy, confocal scanning laser ophthalmoscopy (cSLO), angiography, electroretinography (ERG), and optical coherence tomography (OCT), limitations associated with ex vivo histological preparations can now be circumvented. Inherent methodological limitations confound tissue integrity and curtail longitudinal evaluations within a single subject. Historically, e x vivo histological sectioning is used to study retinal disease in mouse models. Mouse models have been instrumental for understanding pathophysiology in a variety of retinal diseases –. The rapid, high resolution, non-invasive cross-sectional images produced by SD-OCT is an important tool for diagnosing and monitoring posterior segment pathology longitudinally. Spectral domain optical coherence tomography (SD-OCT) is an important imaging modality in clinical ophthalmology and vision science for characterizing morphology and understanding pathophysiological changes within the retina.
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10/18/2023 0 Comments Battle of vienna 1683These conflicts stemmed from neglect to prepare supplies for such a great number of people and animals. The march progressed undisturbed although upon occasions the Poles plundered the local population. In order to implement this plan, the Austrian army was compelled to stop the enemy at Orenburg and Hetman Sieniawski, dispatched to Olomoutz, protected the main column, encumbered with enormous convoys and commanded by the king in person. The choice of Tulln as the site of the crossing was to take the Turks by surprise. The Crown armies did not wait for the Lithuanian forces and set off towards Tulln, where they were to cross the Danube and meet the Austrians and the contingents of the princes of the Reich. Such a composition of the army made it possible to rapidly move towards Vienna. The majority of the forces was composed of the cavalry, in which the Austrians were particularly interested. Earlier, the allies were joined by a 2 000-strong cavalry corps under Hieronim Lubomirski. In a short while, 21 000 soldiers gathered near Cracow. Preparations for war were extremely efficient. Sobieski presented his attitude in a letter to Mikołaj Sieniawski, the field hetman of the Crown: ”Either Vienna will perish or defend itself both shall be inconvenient for us, because it is much better to fight in a foreign land, eating foreign bread and with the assistance of all the forces of the Empire and not only the emperor himself, than to defend oneself at one’s own cost, when our friends and neighbours abandon us if we do not come to their aid immediately”. He was well aware of the gravity of the situation and, simultaneously, of the gains of an alliance with Austria. The imperial diplomats send dramatic pleas, to which the victor of Chocim did not intend to remain indifferent. The sole hope for the town was assistance rendered by the Polish monarch. A regular siege was commenced, but due to the courageous stand of the Viennese it did not bring the Turks the anticipated results. 100 000 men were led by the conceited Kara Mustafa. When the Polish-Austrian alliance was being signed, the Turkish army had set off from Adrianople and in the middle of July, having ravaged a large part of Hungary, it reached the walls of Vienna. The Poles took upon themselves the mobilization of an army of 40 000 men and the Austrians promised to pay 1.2 million zlotys of war subsidies. The pact foresaw a joint battle against the Ottoman state, the avoidance of a separate peace treaty and a siege in case the Turks should attack the capitals of the two states. Only the Turkish threat facing Austria had finally jolted the emperor who was now concerned with obtaining help from the Polish monarch. Jan III had for long wished to achieve such an alliance, but to no avail. In order to avert bad luck and turning the pact into a topic of Fool’s Day jokes, it was antedated and bears the date of 31 March. The military alliance between the Commonwealth and Emperor Leopold I was signed on 1 Aril 1683. 10/18/2023 0 Comments Cardiovascular endurance definitionThis could be walking, housework, gardening, running, hiking, or your daily job.Ī brief description of the aerobic system.Ĭardiorespiratory endurance, like strength, runs on a continuum between the ability to sustain high-intensity activity of short duration (anaerobic) and low-intensity activity of long duration (aerobic). It is simply any exercise that increases heart rate. It is used for moderate intensity exercise and is developed and maintained through cardiovascular exercise as discussed above. Energy is produced by the body breaking down substrates with the aid of oxygen. The Aerobic system is the most complex of the energy systems and most predominant system used to create energy throughout the day. This can produce the by product called lactic acid, and when the build up of lactic acid becomes too great, the body will slow to a rate where it can effectively remove the by product from the body using oxygen. This system is used when doing short activities like sprinting and doesn’t require oxygen to perform. (The body’s process in which oxygen is used to make energy). The anaerobic system is used during high-intensity exercise where energy demands are higher than aerobic metabolism. The body uses two main energy systems, aerobic and anaerobic - which breaks down into two further parts. Examples of aerobic training are foot marching, sustained running, cycling, and swimming.Examples of anaerobic training are speed and interval training, individual movement techniques, and negotiation of obstacles.There are many ways to develop cardio-respiratory fitness through both aerobic and anaerobic conditioning. However, because aerobic fitness is the basis for all training, an endurance based program which utilises anaerobic development alongside this is the best method to maximise performance in the military environment. For those required to perform at a high intensity, short duration and under heavy load, a program based solely on running will not provide sufficient training or support for high performance. Within the military, general training should allow for both aerobic and anaerobic training. Through training you will also likely establish the training level by feel or a perceived rate of exertion as explained above.Īerobic fitness should make up the majority of your training if you want to build your fitness. These percentages are to give you a guide of the approximate level to train in to get the right training response. This is only a guide, it is impossible to accurately obtain specific heart rate ranges without testing within a laboratory with regular intervals. Working out your Heart Rate Zone using Karvonen formulaĪge-Predicted Max HR – 220- _ your age = _ BPMĦ0% max HR = _ max HR x. Takes more effort to talk, slight shortness of breath.Ĭomfortable to maintain for an extended period of time. Only able to complete 1 2 sentences, moderate shortness of breath.Ĭomfortable to maintain for at least 60 mins. Uncomfortable to continue, but able to maintain for 5 - 10 mins.Įxercise is tough, but able to maintain for at least 30 mins. Ratingĭifficult to continue, able to maintain only 10-30 seconds. Below is a guide to both heart rate percentages and the Borg rating of perceived rate of effort and intensity of the exercise. Heart rate monitors are becoming more accurate and these can help you work out the intensity and pace of exercise and exertion required in training to build cardiac endurance. Your heart rate can be used as a measure of exertion during exercise, and can be a helpful way to ensure you are achieving the right training stimulus. This doesn’t just affect physical performance for athletes or military personnel in physically active roles this also applies to those in sedentary roles and individuals within their everyday activities and work. Agility and neuromuscular coordination are reduced.Reaction and movement times are prolonged.Even minor fatigue can hinder total performance: Fatigue is a major deterrent to optimal performance. Low Endurance capacity leads to fatigue, even in activities that are not aerobic. It is common for people to regard cardiovascular endurance as the most important component of fitness to be developed. The other components are: muscular endurance, muscular strength, body composition, and flexibility. Help improve mood, alleviate fatigue and improve sleep qualityĬardiovascular Endurance is one of the five basic components of fitness.Decrease risk of metabolic disease such as diabetes, or heart disease.Improved performance in physically demanding jobs.An increased aerobic capacity and muscle endurance improving ones performance.Ability to maintain a healthy body weight and body fat percentage.A stronger heart and lower resting heart rate.Benefits of cardio respiratory training can lead to: 10/17/2023 0 Comments Citrix receiver chromeCITRIX DISCLAIMS ALL WARRANTIES WHATSOEVER, EXPRESS, IMPLIED, WRITTEN, ORAL OR STATUTORY, INCLUDING WITHOUT LIMITATION WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, TITLE AND NONINFRINGEMENT. You may use and distribute it at your own risk. These software applications are provided to you as is with no representations, warranties or conditions of any kind. cr file with the same example URLs generated by this tool: cr file that can be distributed to the users to configure Receiver for Chrome in case you cannot use Google Policy.ġ) Sample google policy text file with example URLs generated by this tool:Ģ) Sample. This tool can also be used to create/edit the. Please contact your Google Sales Representative to get access. Note: Google policy required for configuring Receiver for Chrome is currently a tech preview capability from Google. The saved policy file created can be directly uploaded in Google Chrome management console to push the policies to Receiver for Chrome. txt google policy file or Enter the appropriate values.Ģ) Select Google policy as the format to save the information.ģ) Click on save button to save the file on the local file system. This tool can be used to create/edit the policy file by following the steps mentioned below:ġ) Upload an already created. To configure Receiver, admin needs to upload a policy text file which contains the settings. This works by using a new feature called App Management which was added in Google Chrome management console for admins to push Chrome app specific policies. cr file to many users, Google policies can be used to configure Receiver for Chrome. cr file using Deploy Receiver for Chrome to your users. Receiver for Chrome can be configured using. cr file exported from Storefront doesn't have rfweb entry and admin needs to add the entry and distribute the file to various users. Today, Citrix Receiver from chrome web store can be configured using. How to Use Receiver for Chrome Configuration cr configuration files easily which can be used to configure Receiver for Chrome. This tool can create and edit google policy and. This is a tool which can be opened in any browser preferably Google Chrome. 10/17/2023 0 Comments Basic differential geometryThey are the closest to the "ordinary" plane and space considered in Euclidean and non-Euclidean geometry. An important class of Riemannian manifolds is formed by the Riemannian symmetric spaces, whose curvature is constant. In higher dimensions, the Riemann curvature tensor is an important pointwise invariant associated to a Riemannian manifold that measures how close it is to being flat. However, Theorema Egregium of Gauss showed that already for surfaces, the existence of a local isometry imposes strong compatibility conditions on their metrics: the Gaussian curvatures at the corresponding points must be the same. Any two regular curves are locally isometric. This notion can also be defined locally, i.e. Many concepts and techniques of analysis and differential equations have been generalized to the setting of Riemannian manifolds.Ī distance-preserving diffeomorphism between Riemannian manifolds is called an isometry. The notion of a directional derivative of a function from the multivariable calculus is extended in Riemannian geometry to the notion of a covariant derivative of a tensor. Various concepts based on length, such as the arc length of curves, area of plane regions, and volume of solids all admit natural analogues in Riemannian geometry. Riemannian geometry generalizes Euclidean geometry to spaces that are not necessarily flat, although they still resemble the Euclidean space at each point "infinitesimally", i.e. Riemannian geometry studies Riemannian manifolds, smooth manifolds with a Riemannian metric, a notion of a distance expressed by means of a positive definite symmetric bilinear form defined on the tangent space at each point. 10/17/2023 0 Comments Covid testing sitePfizer and Moderna have said they are pricing each vaccine dose at over $100. Last Thursday, Moderna and Pfizer both stated that their boosters appeared to work against BA.2.86, saying that the shots triggered a strong antibody response against the variant. Emerging lab data, however, suggests it may not be immune-evasive or transmissible as initially feared. “The new booster will certainly ameliorate protection,” Topol said.Įxperts are also keeping a close eye on BA.2.86 - dubbed “Pirola” by some on social media - an omicron subvariant that initially caused alarm because of its high number of mutations. Eric Topol, executive vice president of Scripps Research in La Jolla, California, said he is “not concerned” about vaccine effectiveness, saying that the vaccines developed so far have consistently shown to provide protection against severe disease, hospitalization and death. Pfizer, Moderna and Novavax have said that their boosters work against EG.5, and Moderna said its booster also works against FL.1.51.ĭr. Both are members of the XBB subvariant family. Another, FL.1.5.1, accounts for about 15% of new cases. One of the predominant strains is called EG.5, which accounts for about 22% of new cases. 2, according to the CDC - other strains in circulation are still closely related to XBB.1.5. While that particular strain is no longer as prevalent - accounting only for about 3% of new Covid cases the week ending Sept. Instead of putting on a status condition or doing team support, it instead applies a sort of "anti-boost" to the other team that acts like a debuff, which can not only reduce ATK, DEF and FCS by 33%, but also overlap and cancel out the effects of the enemy boost, essentially leave them at at huge disadvantage. Packing the standard Flurry + Poise, along with a set of Start Barriers, he's has the presets of a PvP character, but also comes with a unique second SA. Askin: The second meta busting unit on this list, Askin has singlehandedly made the Attribute Strat not only viable, but meta.Jugram is obviously far beyond anyone on this tier list, and probably far beyond any character in BBS history. And Jugram 1v3ing your team isn't just a meme anymore, you can legit be punished for killing other lanes too early if you don't have one of the other 2 characters. Bar another Jugram or a Chad with REALLY high defense, literally nothing else lives long enough to be in the conversation. As you can imagine, games just involve stacking as much Attack as you possibly can on your Jugram and watching everything evaporate. He has Brave Battle Invincibility and Brave Battle Counter. How about straight up invincibility for 10 seconds.? Not enough for you? How about you take damage for attacking him? No, we are not reading you a Looney Tones script. Flurry + Poise at this point is a given, and he gets a nice dose of Pierce Barrier too as an extra finger to SP units (because Ichibei didn't do that enough already). Jugram: Up next on the broken, must have unit list, we have the unbalanced balance character, Jugram.Units below B (Low Tier Booster section included).represents unit(s) released after the previous list was published.Thousand Year Blood War Summons: The Sternritter TO Fierce Battle Summons: Genius There's a lot to unpack here, but hopefully we'll have a good baseline, at least for now before some other invariably broken element comes into play. In light of this news, this will likely be the last full list that we will put out pre-revamp, as there's no telling how drastically those updates could affect the PvP meta (as we've seen with the more widespread distribution of Flurry + Poise, the introduction of Golden Chappies, Link Slot Upgrades and Transcendence in the past). But whatever side of the fence you're on, for the most part the general consensus is that it has been getting somewhat stale, and it seems Klab heard this because they announced during the last Bankai Livestream that PvP was going to receive an overhaul, which at this point is desperately needed. PvP has changed a whole lot in the past few years, for better or for worse. The list may or may not have small changes/edits after release, so keep that in mind. I’m here to bring you the fourteenth iteration and thirteenth update of the official PvP Tier List for the sub. These posts must also be original, unique, and bring something new to the table compared to existing posts.įan art should be original, on-topic, SFW and include a way to generate discussion. Memes should be original, on-topic, SFW and show effort. Low-Effort Content is content in which it is abundantly clear hardly any effort was put into your submission. Spam is content that is repeatedly posted or otherwise deviates from the purpose of the community. Self-Promotion is the act of submitting content for the purpose of any personal benefit. Rule 6: Self-Promotion, Spam, and Low-Effort Submissions ( link) Pull posts unless exceptional (5+, 3 Identicals or 3 Units New Banner Sweep ) will be removed they belong in the brag/flex megathread.Īccount showcases are ONLY permitted in yearly increments (365 days, 730, 1095, etc). Questions "simple/common" belong in the Weekly Q&A megathread. Please refer to our weekly stickied News post to find the Megathreads. Posts that would be more appropriate in a Megathread may be removed. Rule 5: Use the appropriate Megathreads ( link) Therefore all NSFW posts or comments will be removed regardless of type, context, or content. Many of our members and visitors access this subreddit either around family or at work or school. Any content which may tempt or lead users to ToS violating behavior will not be tolerated. No account selling, trading, or giveaways. No encouraging breaking the game’s terms of service. Rule 3: Abide by the game’s Terms of Service ( link) Off-topic posts or posts which belong in r/bleach are subject to removal. Keep all posts relevant to Bleach Brave Souls. If you are the subject of this, report it and do not engage in negative behavior as you are responsible for your own behavior. No hate-speech, racist, sexist, elitist or toxic attitudes. If you have any questions or feel we have made an error in our enforcement of the rules, please send us a modmail. Please read the complete rules before posting or commenting. 10/17/2023 0 Comments Baby skull fractureskeletal dysplasias: one of the major - albeit uncommon - pitfalls in diagnosing NAI (e.g. Schmid-type metaphyseal chondrodysplasia, osteogenesis imperfecta I and IV), which may lack the florid features of the full-blown disease and can be easily confused with NAI.It is an excellent modality to assess for extra-axial blood. MRI is more sensitive for parenchymal injury, but less sensitive for skull fracture. MRI brain can also be performed in an older child or when there is no acute history of head trauma. MRI of the brain and spine should be performed in any child where the CT scan is abnormal. Performing a volume or spiral acquisition with reconstruction at 1 mm or less allows MPR and 3D reconstruction which maximizes skull fracture detection. Dose reduction techniques should be utilized while performing these scans due to risks associated with radiation exposure 12,14. Neuroimaging in NAIĪ CT should be performed in any child who is having a skeletal survey if they are under 1 and in any child between 1 and 2 where there is suspected skull fracture or intracranial injury.Ī CT may reveal extra-axial collections such as a subdural hemorrhage, skull fractures, and parenchymal injury 12,14. Skull fractures also do not heal with periosteal reaction and if seen are less than two weeks old. Metaphyseal (and costochondral junction) injuries do not heal with periosteal reaction and if visible is less than four weeks old. Rib fractures are often missed, hence current practice is to repeat chest films in two weeks to observe any healing fractures 11. Diaphyseal injuries start healing after one week. Traumatic periosteal injuries can be seen on diaphyseal and rib injuries. Traumatic periosteal injury can be seen up to 7 days post-injury (and therefore can be used for dating). The ability to date injuries is critical for medicolegal purposes and thus must be done carefully (please refer to specialist text for specific guidelines). Normally there is high uptake in the epiphyses of bones which should not be confused with a fracture 9. The test becomes positive few hours after injury. It is the most sensitive in detecting fractures of rib, scapula, spine, diaphysis and pelvis. single fractures in diaphysis (spiral humeral fracture is an exception).linear simple fractures of parietal bone.vertebral fractures or vertebral subluxationįractures which have low specificity for NAI are 9:.digital fractures in non-ambulant children.bilateral fractures with fractures of differing ages.depressed fracture ( fracture a la signature)įractures which are moderately specific for NAI are 9:.non-parietal skull fracture (a parietal fracture is more suggestive of accidental injury).skull fracture: suspicious features include:.costochondral junction injuries and/or fractures.although vigorous cardiopulmonary resuscitation can occasionally cause anterior rib fractures, posterior rib fractures do not occur.said to be virtually pathognomonic of NAI.present in up to 39-50% of abused infants metaphyseal fracture (so-called bucket handle fracture or corner fracture).Specific fracturesĪ number of fractures have been recognized as highly specific to non-accidental injuries (rather than accidental injury). Lead markers should be used in skeletal surveys and some institutions will repeat radiographs that do not have a lead marker within the primary field.īone scans are performed in some institutions because of their ability to detect radiographically-occult fractures. The so-called babygram (whereby the entire baby is imaged in one view) is not an acceptable substitute due to the overall lower quality that it produces each anatomical region requires different radiographic exposures to accurately image. despite falls being common, fractures are uncommonĪ skeletal survey is performed in cases of suspected abuse to assess and document the extent of skeletal injuries.history of household falls resulting in fracture.multiple fractures with no family history of osteogenesis imperfecta.injury and history given are inconsistent.injury in the non-ambulatory/totally dependent child.fractures are noted in ~30% (range 11-55%)Ī number of features have been recognized as suspicious:.In 2001 an estimated 903,000 children were victims of maltreatment including: Whilst "Non-Accidental Injury (NAI)" is ubiquitous, Suspected Physical Abuse (SPA) and Inflicted Injury (II) are the preferred terms 10. Over recent years, there have been a number of titles given to the constellation of injuries that are the result of the physical abuse of children. 10/17/2023 0 Comments Bitmart safe moon priceAs of april 2021, users can buy safemoon from pancakeswap and bitmart, and the details are covered below: The very first cryptocurrency released was bitcoin and also now safe moon. How to buy safemoon the very easy way! For more information about how to buy bitcoin and other cryptocurrencies, check out our guide here. This coin has exploded in popularity recently, and for good reason. Safemoon Price Prediction Should You Choose It Over Dogecoin from The exchanges would like you to line up associate degreed fund associate degree account with u.s. We will finish our nft exchange and release our first video game with safemoon integrated. It's a decentralized finance (defi) application that allows a. Open the dapps tab, scroll down below, and search for pancakeswap. 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